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'Devil' loses battle to tumour |
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UTAS
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Thursday, 02 September 2010 |
Devil Facial Tumour Disease is a fatal
condition in Tasmanian Devils and
can be transmitted by biting.
Image: t3rmin4t0r, Flickr CC-licensed.
A Tasmanian devil, known as Cedric, was part of ongoing research for the development of a vaccine against DFTD.
University of Tasmania researchers Associate Professor Greg Woods and Dr
Alex Kreiss of the Menzies Research Institute Tasmania said Cedric, the
Tasmanian devil that had given preliminary indications of an immune
response to Facial Tumour disease, has succumbed to the disease.
In 2007, the Tasmanian devil born in captivity to parents originally
from Tasmania’s west coast, was immunised with dead DFTD tumour cells
and then later challenged with live DFTD tumour cells.
At the time, he showed an immune response to DFTD, which may have
initially protected him from the tumour. Cedric was then rechallenged
with live DFTD tumour cells to determine if the immunisation had
produced long term protection.
“Unfortunately this was not to be the case and in 2008 Cedric had two
small DFTD tumours surgically removed,” Associate Professor of Cancer
and Immunology Greg Woods said.
“Despite appearing healthy and with no signs of disease for almost two
years, a chest x-ray revealed tumour metastasis to his lungs.”
“The decision to euthanise him was made last week.”
“Cedric has played an important part in helping us to understand more
about the disease. He provided hope that an immune response can be
generated against DFTD and his recent battle has strengthened our
resolve to help the devils defeat this disease” Dr Kreiss said.
“While this death is sad news, it is only one part of the puzzle toward
developing a vaccine against DFTD. This was always going to be a long
and difficult task, but the information that Cedric supplied has
provided clues for alternative immunisation strategies.”
Department of Primary Industries, Parks, Water and Environment Director
of Policy and Projects Howel Williams said while the death of the
Tasmanian devil was disappointing, it was important to recognise the
research is one aspect of a number of initiatives in place to assist the
survival of the wild population.
“The Save the Tasmanian Devil Program has always recognised that we are
dealing with a complex disease that can’t rely on single responses to
it,” Mr Williams said.
“That is why the Save the Tasmanian Devil Program has focussed on
developing a range of measures that have been and continue to be
implemented. These include measures such as building an insurance
population that relies on a range of methods of housing them, isolating
wild populations to help break the transmission cycle, disease
suppression and other measures.”
Facial Tumour Disease has caused a major decline in the wild population
of Tasmanian devils with the species now listed as Endangered. The
disease has been recorded across more than 60 per cent of the State in
the wild.
The University of Tasmania is working in partnership with the State and
Federal governments through the Save the Tasmanian Devil Program to help
the survival of Tasmanian Devils.
This program is supported by public funding through the Save the Tasmanian Devil Program Appeal.
Editor's Note:
Original news release can be found here.
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